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Article

Proficient Replication of the Yeast Genome by a Viral DNA Polymerase.

The Journal of biological chemistry - 27 May 2016

Stodola Joseph L, Stith Carrie M, Burgers Peter M

Abstract excerpt

DNA replication in eukaryotic cells requires minimally three B-family DNA polymerases: Pol α, Pol δ, and Pol ϵ. Pol δ replicates and matures Okazaki fragments on the lagging strand of the replication fork. Saccharomyces cerevisiae Pol δ is a three-subunit enzyme (Pol3-Pol31-Pol32). A small C-terminal domain of the catalytic subunit Pol3 carries both iron-sulfur cluster and zinc-binding motifs, which mediate...

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Identifiers

PMID: 27072134
DOI: 10.1074/jbc.M116.728741
PMCID: PMC4882438

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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