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Article

Increased AID Results in Mutations at the CRLF2 Locus Implicated in Latin American ALL Health Disparities

2023-09-11

Abstract excerpt

<title>Abstract</title> <p>Activation-induced cytidine deaminase (AID) is a B cell-specific base editor required during class switch recombination and somatic hypermutation for B cell maturation and antibody diversification. However, it has also been implicated as a factor in the etiology of several B cell malignancies. Evaluating the AID-induced mutation load in patients at-risk for certain types of blood cancer...

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Literature Corpus work
42f960b0-e837-5fd6-8264-f3143c00c8eb
DOI
10.21203/rs.3.rs-3332673/v1
Open publication

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Increased AID Results in Mutations at the CRLF2 Locus Implicated in Latin American ALL Health DisparitiesDOI 10.21203/rs.3.rs-3332673/v1
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