Article

Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells

2025-06-01

Abstract excerpt

<h4>ABSTRACT</h4> Enhancers are key gene regulatory elements that ensure the precise spatiotemporal execution of developmental gene expression programmes. However recent findings indicate that approaches to identify enhancers may not capture the full repertoire of active enhancers in mammalian genomes. Here, we combine massively parallel enhancer assays with chromatin structure and transcriptome profiling to func...

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Literature Corpus work: 3e5b0d07-f963-5f38-975d-5f297e5945c7
DOI: 10.1101/2025.06.01.657118

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