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Article

Functional dissection of the enhancer repertoire in human embryonic stem cells

2017-07-04

Abstract excerpt

<h4>Summary</h4> Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer function requires transcription factor (TF) binding and correlates with histone modifications. However, the extent to which TF binding and histone modifications can functionally define active enhancers remains unclear. Here we combine chromatin immunoprecipitation with a massively parallel reporter assay to iden...

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Literature Corpus work
7d27ef8a-a17f-5f25-b76e-11e107cd4983
DOI
10.1101/146696
Open publication

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Functional dissection of the enhancer repertoire in human embryonic stem cellsDOI 10.1101/146696
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