Article
Super-enhancers are transcriptionally more active and cell-type-specific than stretch enhancers
2018-04-30
Abstract excerpt
<h4>Background</h4> Super-enhancers and stretch enhancers represent classes of transcriptional enhancers that have been shown to control the expression of cell identity genes and carry disease- and trait-associated variants. Specifically, super-enhancers are clusters of enhancers defined based on the binding occupancy of master transcription factors (TFs), chromatin regulators, or chromatin marks, while stretch e...
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Identifiers and source
- Literature Corpus work
- aded8c4e-07eb-526b-8289-a2f33e0ec1d1
- DOI
- 10.1101/310839