Article

An encyclopedia of enhancer-gene regulatory interactions in the human genome

2023-11-13

Abstract excerpt

Identifying transcriptional enhancers and their target genes is essential for understanding gene regulation and the impact of human genetic variation on disease 1–6 . Here we create and evaluate a resource of >13 million enhancer-gene regulatory interactions across 352 cell types and tissues, by integrating predictive models, measurements of chromatin state and 3D contacts, and large-scale genetic perturbations g...

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Literature Corpus work: ba6e41ab-c903-5932-8830-d4efe81a090b
DOI: 10.1101/2023.11.09.563812

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