Transcriptional Enhancers: Bridging the Genome and Phenome.

doi:10.1101/sqb.2015.80.027219

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Article

Transcriptional Enhancers: Bridging the Genome and Phenome.

Cold Spring Harbor symposia on quantitative biology - 1 Jan 2015

Ren Bing, Yue Feng

Abstract excerpt

Enhancers play a major role in animal development by modulating spatiotemporal expression of genes. They interact with sequence-specific transcriptional regulators in response to internal and external cues to bring about transcriptional changes, thus serving as the critical link between an organism's genome and its phenotypic traits. Deciphering the biology of enhancers is a key to understanding the genetic basis...

Topics

Animals
Enhancer Elements, Genetic
Genome
Genotype
Humans
Phenotype
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 26582789
DOI: 10.1101/sqb.2015.80.027219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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