Article

Epigenetic Remodeling in Human Coronary Artery Smooth Muscle Cell Phenotypic Switching

2024-04-14

Abstract excerpt

<h4>Background</h4> Smooth muscle cell (SMC) dedifferentiation contributes to repair and remodeling, but also cardiovascular pathologies. To understand this plasticity, the epigenetic landscape in SMC phenotypic switching was profiled. <h4>Methods</h4> Genome-wide analyses of histone modifications (ChIP-seq), chromatin architecture (ATAC-seq), and transcriptomes (RNA-seq) were performed on human coronary artery...

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Literature Corpus work: 39bc0ddd-f5a2-5ed7-ad66-a8fed7132742
DOI: 10.1101/2024.04.11.589030

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