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Article

Discovery of Transacting Long Noncoding RNAs That Regulate Smooth Muscle Cell Phenotype.

Circulation research - 31 Mar 2023

Shi Huitong, Nguyen Trieu, Zhao Quanyi, Cheng Paul, Sharma Disha, Kim Hyun-Jung, Brian Kim Juyong, Wirka Robert, Weldy Chad S, Monteiro João P, Quertermous Thomas

Abstract excerpt

BACKGROUND: Smooth muscle cells (SMC), the major cell type in atherosclerotic plaques, are vital in coronary artery diseases (CADs). SMC phenotypic transition, which leads to the formation of various cell types in atherosclerotic plaques, is regulated by a network of genetic and epigenetic mechanisms and governs the risk of disease. The involvement of long noncoding RNAs (lncRNAs) has been increasingly identified...

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Share to Myocytes, Smooth Muscle
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Plaque, Atherosclerotic

Share to RNA, Long Noncoding

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Source

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Identifiers

PMID: 36852690
DOI: 10.1161/CIRCRESAHA.122.321960
PMCID: PMC11056793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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