Article

Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation

2021-12-06

Abstract excerpt

During activation, T cells undergo extensive changes in gene expression which shape the properties of cells to exert their effector function. Therefore, understanding the genetic regulation of gene expression during T cell activation provides essential insights into how genetic variants influence the response to infections and immune diseases. We generated a single-cell map of expression quantitative trait loci (e...

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Literature Corpus work: 3512da62-530a-5d24-91cf-94d7d1a30067
DOI: 10.1101/2021.12.06.470953

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