Article

Mapping interindividual dynamics of innate immune response at single-cell resolution

2021-09-01

Abstract excerpt

Common genetic variants modulate the cellular response to viruses and are implicated in a range of immune pathologies, including infectious and autoimmune diseases. The transcriptional antiviral response is known to vary between infected cells from a single individual, yet how genetic variants across individuals modulate the antiviral response (and its cell-to-cell variability) is not well understood. Here, we tri...

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Literature Corpus work: 011f27fb-fa15-53a1-9312-a5370b30211e
DOI: 10.1101/2021.09.01.457774

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