Article

The Impact of Selection Bias on Genetic Prediction Using the Bipolar Polygenic Risk Score in First-Admission Psychosis

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>Polygenic risk scores (PRS) have potential utility as biomarkers of psychiatric disorders. However, while the schizophrenia (SZ) PRS has been consistently associated with case-control status and a more severe course of illness, the associations between the bipolar (BP) PRS and markers of bipolar disorder vary considerably between studies, with studies of population and case-control samp...

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Literature Corpus work: 34925cc6-233d-5d4d-aaaa-66d3717171ae
DOI: 10.21203/rs.3.rs-4536236/v1

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