Article

Use of multiple Polygenic Risk Scores for distinguishing Schizophrenia-spectrum disorder and Affective psychosis categories; the EUGEI study

2021-04-05

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia (SZ), Bipolar Disorder (BD) and Depression (D) run in families. This susceptibility is partly due to hundreds or thousands of common genetic variants, each conferring a fractional risk. The cumulative effects of the associated variants can be summarised as a polygenic risk score (PRS). Using data from the EUGEI case-control study, we aimed to test whether PRSs for three major psychi...

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Literature Corpus work: 135af44f-5363-5c75-941e-d0a92494f5b5
DOI: 10.1101/2021.03.31.21254574

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