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Article

Polygenic risk score and the psychosis continuum model.

Acta psychiatrica Scandinavica - 1 Oct 2014

Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen O A

Abstract excerpt

OBJECTIVE: Schizophrenia (SZ) and bipolar disorder (BD) are heritable, polygenic disorders with shared clinical characteristics and genetic risk indicating a psychosis continuum. This is the first study using polygenic risk score (PGRS) to investigate the localization of diagnostic subcategories along the entire psychosis spectrum. METHOD: Based on results from the Psychiatric Genomics Consortium (PGC), we...

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Identifiers

PMID: 24961959
DOI: 10.1111/acps.12307

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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