Article
The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review.
Schizophrenia research - 1 Jul 2018
Mistry Sumit, Harrison Judith R, Smith Daniel J, Escott-Price Valentina, Zammit Stanley
Abstract excerpt
Studying the phenotypic manifestations of increased genetic liability for schizophrenia can increase our understanding of this disorder. Specifically, information from alleles identified in genome-wide association studies can be collapsed into a polygenic risk score (PRS) to explore how genetic risk is manifest within different samples. In this systematic review, we provide a comprehensive assessment of studies...
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