Article

Rapid high-resolution measurement of DNA replication timing by droplet digital PCR

2017-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Genomes are replicated in a reproducible temporal pattern. Current methods for assaying allele replication timing are time consuming and/or expensive. These include high-throughput sequencing which can be used to measure DNA copy number as a proxy for allele replication timing. Here, we use droplet digital PCR to study DNA replication timing at multiple loci in budding yeast and human cells. We...

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Literature Corpus work: 31c2c765-1d67-502b-be73-d4bca426f242
DOI: 10.1101/208546

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