Article

Kronos scRT: a uniform framework for single-cell replication timing analysis

2021-09-03

Abstract excerpt

Mammalian genomes are replicated in a cell-type specific order and in coordination with transcription and chromatin organization. Although the field of replication is also entering the single-cell era, current studies require cell sorting, individual cell processing and have yielded a limited number (<100) of cells. Here, we have developed Kronos scRT ( https://github.com/CL-CHEN-Lab/Kronos_scRT ), a software for...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 807ec329-c60c-56aa-bb6c-1b5f0b83b718
DOI: 10.1101/2021.09.01.458599

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Kronos scRT: a uniform framework for single-cell replication timing analysisDOI 10.1101/2021.09.01.458599Read

High-throughput analysis of single human cells reveals the complex nature of DNA replication timing controlSemantic proximity Read

Development of a Novel Single Cell Multiomics Approach for Simultaneous Analysis of Replication Timing and Gene ExpressionSemantic proximity Read

Repli-seq: genome-wide analysis of replication timing by next-generation sequencingSemantic proximity Read

Novel Single-Cell Multiomics Approach to Analyze Replication Timing and Gene Expression in Mouse Preimplantation EmbryosSemantic proximity Read

Single cell multiomics approach to analyze replication timing and gene expression in mouse preimplantation embryosSemantic proximity Read

Unraveling the timeline of gene expression: A pseudotemporal trajectory analysis of single-cell RNA sequencing dataSemantic proximity Read

Optimized Repli-seq: Improved DNA Replication Timing Analysis by Next-Generation SequencingSemantic proximity Read

High Resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cellsSemantic proximity Read

Unraveling the timeline of gene expression: a pseudo-temporal trajectory analysis of single-cell RNA sequencing dataSemantic proximity Read

Rapid high-resolution measurement of DNA replication timing by droplet digital PCR.Semantic proximity Read

High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cellsSemantic proximity Read

Rapid high-resolution measurement of DNA replication timing by droplet digital PCRSemantic proximity Read