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Article

Rapid high-resolution measurement of DNA replication timing by droplet digital PCR.

Nucleic acids research - 2 Nov 2018

Batrakou Dzmitry G, Heron Emma D, Nieduszynski Conrad A

Abstract excerpt

Genomes are replicated in a reproducible temporal pattern. Current methods for assaying allele replication timing are time consuming and/or expensive. These include high-throughput sequencing which can be used to measure DNA copy number as a proxy for allele replication timing. Here, we use droplet digital PCR to study DNA replication timing at multiple loci in budding yeast and human cells. We establish that the...

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Identifiers

PMID: 29986073
DOI: 10.1093/nar/gky590
PMCID: PMC6212846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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