Article

CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells

2020-06-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Drawing genotype-to-phenotype maps in tumors is of paramount importance for understanding tumor heterogeneity. Assignment of single cells to their tumor clones of origin can be approached by matching the genotypes of the clones to the mutations found in RNA sequencing of the cells. The confidence of the cell-to-clone mapping can be increased by accounting for additional meas...

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Literature Corpus work: 25b50ab7-f581-530f-8715-1b6b0ff01420
DOI: 10.1101/2020.06.05.134452

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