Article

MuClone: Somatic mutation detection and classification through probabilistic integration of clonal population structure

2017-09-20

Abstract excerpt

Accurate detection and classification of somatic single nucleotide variants (SNVs) is important in defining the clonal composition of human cancers. Existing tools are prone to miss low prevalence mutations and methods for classification of mutations into clonal groups across the whole genome are underdeveloped. Increasing interest in deciphering clonal population dynamics over multiple samples in time or anatomic...

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Literature Corpus work: ae41d6ef-6407-55d0-a05f-217723eee39f
DOI: 10.1101/191759

Open publication

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