Article

CaClust: linking genotype to transcriptional heterogeneity of follicular lymphoma using BCR and exomic variants

2024-04-28

Abstract excerpt

Tumor tissues exhibit high genotypic and transcriptional heterogeneity, resulting from tumor evolution and affecting cancer progression and treatment. These two types of heterogeneity in follicular lymphoma were so far predominantly studied in separation. To comprehensively investigate the evolution and genotype to phenotype maps in follicular lymphoma, we introduce CaClust, a probabilistic graphical model that in...

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Literature Corpus work: b656a0ed-b6a7-5faa-a0a5-20b1b9925fc1
DOI: 10.1101/2024.04.24.590966

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