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Article

True causal effect size heterogeneity is not required to explain trans-ethnic differences in GWAS signals

2016-11-02

Abstract excerpt

Through genome-wide association studies (GWASs), researchers have identified hundreds of genetic variants associated with particular complex traits. Previous studies have compared the pattern of association signals across different populations in real data, and these have detected differences in the strength and sometimes even the direction of GWAS signals. These differences could be due to a combination of (1) la...

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Literature Corpus work
19c6eb14-a81f-5384-a7ad-49d6345670e4
DOI
10.1101/085092
Open publication

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True causal effect size heterogeneity is not required to explain trans-ethnic differences in GWAS signalsDOI 10.1101/085092
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