Article
Multiethnic genetic association studies improve power for locus discovery.
PloS one - 8 Sept 2010
Pulit Sara L, Voight Benjamin F, de Bakker Paul I W
Abstract excerpt
To date, genome-wide association studies have focused almost exclusively on populations of European ancestry. These studies continue with the advent of next-generation sequencing, designed to systematically catalog and test low-frequency variation for a role in disease. A complementary approach would be to focus further efforts on cohorts of multiple ethnicities. This leverages the idea that population genetic...
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