Article

TEMR: Trans-ethnic Mendelian Randomization Method using Large-scale GWAS Summary Datasets

2024-06-17

Abstract excerpt

Available large-scale GWAS summary datasets predominantly stem from European populations, while sample sizes for other ethnicities, notably Central/South Asian, East Asian, African, Hispanic, etc. remain comparatively limited, which induces the low precision of causal effect estimation within these ethnicities using Mendelian Randomization (MR). In this paper, we propose a Trans-ethnic MR method called TEMR to imp...

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Literature Corpus work: 28654c77-ab3e-51f3-9d6e-625842cedde1
DOI: 10.1101/2024.06.16.24308874

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