Article
Transethnic differences in GWAS signals: A simulation study.
Annals of human genetics - 1 Sept 2018
Zanetti Daniela, Weale Michael E
Abstract excerpt
Genome-wide association studies (GWASs) have allowed researchers to identify thousands of single nucleotide polymorphisms (SNPs) and other variants associated with particular complex traits. Previous studies have reported differences in the strength and even the direction of GWAS signals across different populations. These differences could be due to a combination of (1) lack of power, (2) allele frequency...
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