Article
Transethnic Genetic-Correlation Estimates from Summary Statistics.
American journal of human genetics - 7 Jul 2016
Brown Brielin C, Ye Chun Jimmie, Price Alkes L, Zaitlen Noah
Abstract excerpt
The increasing number of genetic association studies conducted in multiple populations provides an unprecedented opportunity to study how the genetic architecture of complex phenotypes varies between populations, a problem important for both medical and population genetics. Here, we have developed a method for estimating the transethnic genetic correlation: the correlation of causal-variant effect sizes at SNPs...
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