Article
Clarifying the causes of consistent and inconsistent findings in genetics.
Genetic epidemiology - 1 Oct 2022
Dattani Saloni, Howard David M, Lewis Cathryn M, Sham Pak C
Abstract excerpt
As research in genetics has advanced, some findings have been unexpected or shown to be inconsistent between studies or datasets. The reasons these inconsistencies arise are complex. Results from genetic studies can be affected by various factors including statistical power, linkage disequilibrium, quality control, confounding and selection bias, as well as real differences from interactions and effect modifiers,...
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