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Article

Impact of cross-ancestry genetic architecture on GWASs in admixed populations.

American journal of human genetics - 1 Jun 2023

Mester Rachel, Hou Kangcheng, Ding Yi, Meeks Gillian, Burch Kathryn S, Bhattacharya Arjun, Henn Brenna M, Pasaniuc Bogdan

Abstract excerpt

Genome-wide association studies (GWASs) have identified thousands of variants for disease risk. These studies have predominantly been conducted in individuals of European ancestries, which raises questions about their transferability to individuals of other ancestries. Of particular interest are admixed populations, usually defined as populations with recent ancestry from two or more continental sources. Admixed...

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Identifiers

PMID: 37224807
DOI: 10.1016/j.ajhg.2023.05.001
PMCID: PMC10257009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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