Article

Network analysis reveals strain-dependent response to misfolded tau aggregates

2023-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Mouse genetic backgrounds have been shown to modulate amyloid accumulation and propagation of tau aggregates. Previous research into these effects has highlighted the importance of studying the impact of genetic heterogeneity on modeling Alzheimer’s disease. However, it is unknown what mechanisms underly these effects of genetic background on modeling Alzheimer’s disease, specifically tau aggreg...

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Literature Corpus work: 16f00c93-4425-5661-9bc5-c36a772749bf
DOI: 10.1101/2023.01.28.526029

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