Article

Systematic Phenotyping and Characterization of the 5xFAD mouse model of Alzheimer’s Disease

2021-02-19

Abstract excerpt

Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as Alzheimer’s disease in which numerous models are being generated, a challenging first step is to identify the most appropriate model and age to effectively evaluate new therapeutic approaches. Here we conducted a detailed phenotypic characterization of the 5xFAD m...

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Literature Corpus work: 537206f8-1756-54fe-9acc-aa1f5898edf2
DOI: 10.1101/2021.02.17.431716

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