Article

Microglia Adopt Temporally Specific States after Irradiation, Correlating with Neuronal Asynchrony

2025-02-16

Abstract excerpt

Cranial radiotherapy causes progressive neurocognitive impairments in cancer survivors. Neuroinflammation is a key contributor, but its dynamics and consequences for brain function remain poorly understood. Here, we performed comprehensive longitudinal profiling from 6 hours to 1 year after irradiation (IR) of the mouse hippocampus, using transcriptomic, protein, and histological analyses. We identified delayed mi...

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Literature Corpus work: 00e53ca7-f139-5ec8-a72a-2d1cd1f3c05e
DOI: 10.1101/2025.02.15.638339

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