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Article

Regionally distinct responses of microglia and glial progenitor cells to whole brain irradiation in adult and aging rats.

PloS one - 1 Jan 2012

Hua Kun, Schindler Matthew K, McQuail Joseph A, Forbes M Elizabeth, Riddle David R

Abstract excerpt

Radiation therapy has proven efficacy for treating brain tumors and metastases. Higher doses and larger treatment fields increase the probability of eliminating neoplasms and preventing reoccurrence, but dose and field are limited by damage to normal tissues. Normal tissue injury is greatest duri...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23300752
DOI: 10.1371/journal.pone.0052728
PMCID: PMC3530502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23300752-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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