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Article

Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative properties

2025-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Phagocytosis of apoptotic cells, or efferocytosis, is a tightly regulated process that ensures tissue homeostasis and prevents mounting inflammatory responses. In the brain parenchyma, it is executed by microglia, which are encumbered by large numbers of apoptotic debris generated during development, in adult neurogenic niches, aging, and brain diseases. Emerging evidence suggest that phagocytos...

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Identifiers and source

Literature Corpus work
882c3a55-46b6-53c6-9d0d-1fbd3e0567cb
DOI
10.1101/2025.09.18.676800
Open publication

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Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative propertiesDOI 10.1101/2025.09.18.676800
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