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Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative properties

2025-10-09

Abstract excerpt

<title>Abstract</title> <p>Phagocytosis of apoptotic cells, or efferocytosis, is a tightly regulated process that ensures tissue homeostasis and prevents mounting inflammatory responses. In the brain parenchyma, it is executed by microglia, which are encumbered by large numbers of apoptotic debris generated during development, in adult neurogenic niches, aging, and brain diseases. Emerging evidence suggest that p...

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Literature Corpus work
3d9a930d-a74d-5dac-a3c4-5c562b0cadc9
DOI
10.21203/rs.3.rs-7743374/v1
Open publication

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Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative propertiesDOI 10.21203/rs.3.rs-7743374/v1
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