Article
Analyzing microglial phenotypes across neuropathologies: a practical guide.
Acta neuropathologica - 1 Dec 2021
Schwabenland Marius, Brück Wolfgang, Priller Josef, Stadelmann Christine, Lassmann Hans, Prinz Marco
Abstract excerpt
As extremely sensitive immune cells, microglia act as versatile watchdogs of the central nervous system (CNS) that tightly control tissue homeostasis. Therefore, microglial activation is an early and easily detectable hallmark of virtually all neuropsychiatric, neuro-oncological, neurodevelopmental, neurodegenerative and neuroinflammatory diseases. The recent introduction of novel high-throughput technologies and...
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