Identification of SEC12, SED4, truncated SEC16, and EKS1/HRD3 as multicopy suppressors of ts mutants of Sar1 GTPase.

doi:10.1093/oxfordjournals.jbchem.a022249

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Identification of SEC12, SED4, truncated SEC16, and EKS1/HRD3 as multicopy suppressors of ts mutants of Sar1 GTPase.

Journal of biochemistry - 1 Jan 1999

Saito Y, Yamanushi T, Oka T, Nakano A

Abstract excerpt

The yeast SAR1 gene encodes a low-molecular-weight GTPase which is essential for the formation of transport vesicles from the endoplasmic reticulum (ER). To understand how the Sar1p function is regulated in its GTPase cycle, we searched for multicopy suppressors of sar1 temperature-sensitive muta...

Topics

Endoplasmic Reticulum
Fungal Proteins
GTP-Binding Proteins
Gene Dosage
Genes, Suppressor
Guanine Nucleotide Exchange Factors
Membrane Glycoproteins
Membrane Proteins
Monomeric GTP-Binding Proteins
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Vesicular Transport Proteins

Source

Open in PubMed

Identifiers

PMID: 9880808
DOI: 10.1093/oxfordjournals.jbchem.a022249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9880808-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics