Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation.

doi:10.1093/oxfordjournals.jbchem.a021460

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Article

Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation.

Journal of biochemistry - 1 Sept 1996

Nakano A

Abstract excerpt

The product of the yeast SEC12 gene is the most upstream player as far as we know in the events of vesicle budding from the endoplasmic reticulum membrane. To understand how the Sec12p function could be regulated, I identified three extragenic suppressor mutations of the sec12 ts mutation. RST1DS...

Topics

Endoplasmic Reticulum
Fungal Proteins
Genes, Dominant
Genes, Fungal
Genes, Recessive
Genotype
Guanine Nucleotide Exchange Factors
Membrane Glycoproteins
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Suppression, Genetic

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