Article
[Genetic alterations in the region of the p53 gene on human chromosome 17 in colorectal cancer].
Genetika - 1 Aug 1998
Kashkin K N, Fleĭshman E V, Chumakov P M, Perevoshchikov A G
Abstract excerpt
Most colorectal tumors are characterized, among other genetic alterations, by allele loss of the genes located on the short arm of chromosome 17 (17p13.1), including the p53 suppressor gene. In ovarian and mammary-gland tumors, deletions of another candidate tumor-suppressor gene, located in the...
Topics
- Alleles
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 17
- Colorectal Neoplasms
- Gene Deletion
- Genes, p53
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Translocation, Genetic
