Article
Allelic loss on chromosome 17 in human ovarian cancer.
International journal of cancer - 22 Apr 1993
Phillips N, Ziegler M, Saha B, Xynos F
Abstract excerpt
In order to identify a common region of deletion on chromosome 17 potentially containing a tumor-suppressor gene, 27 ovarian carcinomas and 3 ovarian tumors of low malignant potential (LMP) were examined for loss of heterozygosity (LOH) at 6 p arm and 10 q arm loci. Ninety percent of all tumors h...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Heterozygote
- Humans
- Lymphatic Metastasis
- Middle Aged
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Ovarian Neoplasms
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
