Article
Allelic loss on chromosome 17 in human ovarian cancer.
International journal of cancer - 22 Apr 1993
Phillips N, Ziegler M, Saha B, Xynos F
Abstract excerpt
In order to identify a common region of deletion on chromosome 17 potentially containing a tumor-suppressor gene, 27 ovarian carcinomas and 3 ovarian tumors of low malignant potential (LMP) were examined for loss of heterozygosity (LOH) at 6 p arm and 10 q arm loci. Ninety percent of all tumors had deletions at one or more loci. On the p arm, there was a single near-common region of deletion on 17p13.3...
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