Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.

Article

Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.

Oncogene - 1 Oct 1992

Eccles D M, Russell S E, Haites N E, Atkinson R, Bell D W, Gruber L, Hickey I, Kelly K, Kitchener H, Leonard R

Abstract excerpt

We have studied 146 ovarian tumours (94 carcinomas, 22 tumours of low malignant potential and 30 benign tumours) for evidence of allele loss on chromosome 17p and 17q sufficient to imply the proximity of a tumour-suppressor gene. We have examined two polymorphic loci (YNZ22.2 and BHP53) on 17p13...

Topics

Alleles
Chromosome Aberrations
Chromosomes, Human, Pair 17
Female
Genes, Tumor Suppressor
Heterozygote
Humans
Ovarian Neoplasms

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