Article
Allelic loss in ovarian cancer.
International journal of cancer - 19 Jun 1993
Yang-Feng T L, Han H, Chen K C, Li S B, Claus E B, Carcangiu M L, Chambers S K, Chambers J T, Schwartz P E
Abstract excerpt
Loss of heterozygosity (LOH) was examined at 86 loci distributed on every chromosomal arm in 50 human ovarian tumors. Frequent allele losses were observed on chromosomes 13q (42%), 17p (42%), 17q (45%), and Xp (41%). Deletion mapping on chromosome 17 revealed a candidate gene on the long arm dist...
Topics
- Alleles
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 3
- DNA, Neoplasm
- Female
- Genetic Markers
- Humans
- Nucleic Acid Hybridization
- Ovarian Neoplasms
- Polymorphism, Restriction Fragment Length
