Article
p53 mutation in epithelial ovarian carcinoma and borderline ovarian tumor.
Cancer genetics and cytogenetics - 1 Nov 1995
Lee J H, Kang Y S, Park S Y, Kim B G, Lee E D, Lee K H, Park K B, Kavanagh J J, Wharton J T
Abstract excerpt
We have investigated a series of 19 human ovarian carcinomas and 17 borderline ovarian tumors to determine the loss of heterozygosity on chromosome 17p and possible concurrent p53 mutations. Allelic losses were assessed using restriction fragment length polymorphism study, and p53 gene mutations were detected by single strand conformation polymorphism analysis and by direct sequencing. In addition, we stained the...
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