Article
Allelic loss of the p53 gene in colorectal cancer.
Annals of the Academy of Medicine, Singapore - 1 May 1995
Smith D R, Khine K, Goh H S
Abstract excerpt
The loss of specific chromosomal loci in cancers is indicative that the region contains a tumour suppressor gene. Allelic loss of chromosome 17p has been shown to occur in a wide variety of cancers such as lung, breast, colon, ovary and brain and, until recently, the gene believed to be involved was the p53 tumour suppressor gene. However, more recent studies have shown that the area deleted in some of these...
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