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Article

Allelic loss on chromosome 17p and p53 mutations in human endometrial carcinoma of the uterus.

Cancer research - 15 Oct 1991

Okamoto A, Sameshima Y, Yamada Y, Teshima S, Terashima Y, Terada M, Yokota J

Abstract excerpt

To understand the involvement of allelic losses and inactivation of tumor suppressor genes for the development of endometrial carcinoma of the uterus (EC), 24 cases of EC were examined for loss of heterozygosity (LOH) using a total of 57 polymorphic DNA markers covering all 23 pairs of chromosomes. LOH was observed at 27 loci on 10 different chromosomes, i.e., chromosomes 1, 3, 6, 11, 13, 15, 17, 18, 20, and 21,...

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 17
Codon
Female
Genes, p53
Heterozygote
Humans
Mutation
Polymerase Chain Reaction
Uterine Neoplasms

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PMID: 1913680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1913680-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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