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Article

Domain 5 binds near a highly conserved dinucleotide in the joiner linking domains 2 and 3 of a group II intron.

RNA (New York, N.Y.) - 1 Feb 1998

Podar M, Zhuo J, Zhang M, Franzen J S, Perlman P S, Peebles C L

Abstract excerpt

Photocrosslinking has identified the joiner between domains 2 and 3 [J(23)] as folding near domain 5 (D5), a highly conserved helical substructure of group II introns required for both splicing reactions. D5 RNAs labeled with the photocrosslinker 4-thiouridine (4sU) reacted with highly conserved nucleotides G588 and A589 in J(23) of various intron acceptor transcripts. These conjugates retained some ribozyme...

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Identifiers

PMID: 9570315
PMCID: PMC1369604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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