Activation of the catalytic core of a group I intron by a remote 3' splice junction.

doi:10.1101/gad.6.8.1373

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Article

Activation of the catalytic core of a group I intron by a remote 3' splice junction.

Genes & development - 1 Aug 1992

Michel F, Jaeger L, Westhof E, Kuras R, Tihy F, Xu M Q, Shub D A

Abstract excerpt

Over 1000 nucleotides may separate the ribozyme core of some group I introns from their 3' splice junctions. Using the sunY intron of bacteriophage T4 as a model system, we have investigated the mechanisms by which proximal splicing events are suppressed in vitro, as well as in vivo. Exon ligatio...

Topics

Base Sequence
DNA Mutational Analysis
Escherichia coli
Genes, Viral
Introns
Magnesium
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Plasmids
RNA Splicing
RNA, Catalytic
RNA, Messenger
T-Phages

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