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Article

Activation of the catalytic core of a group I intron by a remote 3' splice junction.

Genes & development - 1 Aug 1992

Michel F, Jaeger L, Westhof E, Kuras R, Tihy F, Xu M Q, Shub D A

Abstract excerpt

Over 1000 nucleotides may separate the ribozyme core of some group I introns from their 3' splice junctions. Using the sunY intron of bacteriophage T4 as a model system, we have investigated the mechanisms by which proximal splicing events are suppressed in vitro, as well as in vivo. Exon ligation as well as cleavage at the 5' splice site are shown to require long-range pairing between one of the peripheral...

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Identifiers

PMID: 1644285
DOI: 10.1101/gad.6.8.1373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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