Article
Parametric survival analysis for gating kinetics of single potassium channels.
Brain research - 3 Oct 1997
Shao X M
Abstract excerpt
The gating mechanism and the role of the S4 region in the activation of Shaker potassium channel was studied by statistical analysis on the wild type and mutant channels which have mutations in the S4 region. Single channel currents were recorded with the patch-clamp technique. The first latency time was analyzed with a parametric survival time regression model in which the generalized gamma distribution for the...
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