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Article

The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.

eLife - 6 Oct 2016

Zhao Juan, Blunck Rikard

Abstract excerpt

Domains in macromolecular complexes are often considered structurally and functionally conserved while energetically coupled to each other. In the modular voltage-gated ion channels the central ion-conducting pore is surrounded by four voltage sensing domains (VSDs). Here, the energetic coupling is mediated by interactions between the S4-S5 linker, covalently linking the domains, and the proximal C-terminus. In...

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Identifiers

PMID: 27710769
DOI: 10.7554/eLife.18130
PMCID: PMC5092046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.PMID 27710769Read ↗

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