Article
Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.
Neuron - 1 Oct 1995
Baukrowitz T, Yellen G
Abstract excerpt
Voltage-activated K+ currents and their inactivation properties are important for controlling frequency-dependent signaling in neurons and other excitable cells. Two distinct molecular mechanisms for K+ channel inactivation have been described: N-type, which involves rapid occlusion of the open channel by an intracellular tethered blocker, and C-type, which involves a slower change at the extracellular mouth of...
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