Article
Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.
Neuron - 1 Oct 1995
Baukrowitz T, Yellen G
Abstract excerpt
Voltage-activated K+ currents and their inactivation properties are important for controlling frequency-dependent signaling in neurons and other excitable cells. Two distinct molecular mechanisms for K+ channel inactivation have been described: N-type, which involves rapid occlusion of the open c...
Topics
- Cell Line
- Electric Conductivity
- Embryo, Mammalian
- Gene Deletion
- Humans
- Ion Channel Gating
- Kidney
- Kinetics
- Mutation
- Potassium
- Potassium Channels
- Transfection