Article
Regulation of Shaker K+ channel inactivation gating by the cAMP-dependent protein kinase.
Neuron - 1 May 1994
Drain P, Dubin A E, Aldrich R W
Abstract excerpt
In response to depolarization of the membrane potential, Shaker K+ channels undergo a series of voltage-dependent conformational changes, from resting to open conformations followed by a rapid transition into a long-lived closed conformation, the N-type inactivated state. Application of phosphata...
Topics
- Adenosine Triphosphate
- Alanine
- Alkaline Phosphatase
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Cyclic AMP-Dependent Protein Kinases
- DNA Primers
- Drosophila
- Escherichia coli
- Female
- Genetic Variation
- Ion Channel Gating
- Kinetics
- Membrane Potentials
- Molecular Sequence Data
- Mutagenesis, Site-Directed